Dihydrocyclosporin A

CAS: 59865-15-5

Ref. 3D-FD21913

Información del producto

• Nombre: Dihydrocyclosporin A
• Sinónimos: 6-[(2S,3R,4R)-3-Hydroxy-4-methyl-2-(methylamino)octanoic acid]cyclosporin A
• Marca: Biosynth
• Descripción: Dihydrocyclosporin A is an immunosuppressant, which is a cyclic undecapeptide derived from fungal metabolites, specifically from the soil fungus Tolypocladium inflatum. This compound functions through the inhibition of calcineurin, which is a crucial phosphatase involved in the activation of T-cells. By binding to the intracellular protein cyclophilin, Dihydrocyclosporin A forms a complex that inhibits calcineurin activity, subsequently blocking the transcription of interleukin-2 and other cytokines essential for T-cell proliferation.

Propiedades químicas

• Peso molecular: 1,204.63 g/mol
• Fórmula: C₆₂H₁₁₃N₁₁O₁₂
• Pureza: Min. 95 Area-%
• Color/Forma: Powder