Darunavir Ethanolate

CAS: 635728-49-3

Ref. 3D-FD64995

Información del producto

• Nombre: Darunavir Ethanolate
• Sinónimos: Prezista, Unii-33O78Xf0Bw, Carbamic acid, ((1S,2R)-3-(((4-aminophenyl)sulfonyl)(2-methylpropyl)amino)-2-hydroxy-1-(phenylmethyl)propyl)-, (3R,3aS,6aR)-hexahydrofuro(2,3-b)furan-3-yl ester, compd. with ethanol (1:1)

Descripción

Darunavir is a HIV-1 protease inhibitor used orally in the treatment of patients with multi-drug resistant HIV-1 infection (Ghosh, 2007). It has also been shown to be effective against other infectious diseases such as hepatitis C virus and SARS coronavirus. Metabolized by cytochrome P450 3A (CYP3A) isoenzymes, darunavir is often administered together with ritonavir that prolongs its bioavaiability, giving a terminal elimination half-life (t1/2) of 15 hours (Back, 2008). The effect of darunavir on natural compounds such as matrix proteins and toll-like receptor activity has also been studied via high performance liquid chromatography (HPLC) experiments.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 593.73 g/mol
• Fórmula: C₂₇H₃₇N₃O₇S·C₂H₆O
• Pureza: Min. 95%
• Color/Forma: White Powder