SU 5416

CAS: 204005-46-9

Ref. 3D-FD65177

Información del producto

• Nombre: SU 5416
• Sinónimos: 1,3-Dihydro-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]-2H-indol-2-one, (3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-1,3-dihydro-2H-indol-2-one, (3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-1H-indol-2-one, (Z)-3-(3,5-Dimethylpyrrol-2-ylmethylene)indolin-2-one, 2H-Indol-2-one, 3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-, 3-((2,4-Dimethylpyrrol-5-YL)METHYLIDENYL)-2-indolonone, 3-(3,5-Dimethyl-1H-pyrrol-2-ylmethylene)-1,3-dihydroindol-2-one, 3-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2H-indol-2-one, 3-[(3,5-Dimethylpyrrol-2-yl)methylene]indolin-2-one, Nsc-696819, Semaxanib, Semaxinib, Semoxind, Su-5416, Sugen 5416, Tsu-16, VEGFR2 receptor tyrosine kinase III

Descripción

Inhibitor of Flk-1/KDR receptor tyrosine kinases, a vascular endothelial growth factor receptor (VEGF) receptor expressed on precursor and mature forms of endothelial cells. SU 5416 also inhibits other tyrosine kinases, including c-KIT and FLT-3. Has therapeutic potential as an anti-angiogenic agent for the treatment of cancer.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 238.28 g/mol
• Fórmula: C₁₅H₁₄N₂O
• Pureza: Min. 95%
• Color/Forma: Powder
• InChI: InChI=1S/C15H14N2O/c1-9-7-10(2)16-14(9)8-12-11-5-3-4-6-13(11)17-15(12)18/h3-8,16H,1-2H3,(H,17,18)/b12-8-
• Clave InChI: InChIKey=WUWDLXZGHZSWQZ-WQLSENKSSA-N
• SMILES: Cc1cc(C)c(/C=C2\C(=O)Nc3ccccc32)[nH]1