2,4-Difluoro-5-Methyl-Benzonitrile
CAS: 329314-68-3
Ref. 3D-FD81861
| 1g | A consultar | |
| 5g | A consultar | |
| 500mg | A consultar |
Información del producto
- 2,4-Difluoro-5-methylbenzonitrile
- Benzonitrile, 2,4-difluoro-5-methyl-
- Ncr Bf Df E1
2,4-Difluoro-5-methylbenzonitrile (2,4-DMN) is a prodrug that is metabolized in vivo to its active form, 2,5-difluorobenzoic acid. 2,4-DMN inhibits the activity of the NS5B polymerase enzyme in the replication of human immunodeficiency virus type 1 (HIV-1) by competitive inhibition and prevents viral RNA synthesis. This compound has been shown to be orally bioavailable and efficacious against HIV-1 in monkeys. 2,4-DMN also inhibits the activity of other types of viruses with a nonpolar active site such as herpes simplex virus type 1 and varicella zoster virus.
2,4-DMN has been found to have little or no inhibitory effects on mammalian DNA polymerases α or β when used at concentrations up to 10 μM.
Propiedades químicas
Consulta técnica sobre: 3D-FD81861 2,4-Difluoro-5-Methyl-Benzonitrile
Si desea solicitar un presupuesto o realizar un pedido, por favor añada los productos deseados a su carrito y solicite un presupuesto o pedido desde el carrito. Es más rápido, más barato, y podrá beneficiarse de los descuentos y las ventajas disponibles.
