Eniluracil

CAS: 59989-18-3

Ref. 3D-FE13804

Información del producto

• Nombre: Eniluracil
• Sinónimos: 2,4(1H,3H)-Pyrimidinedione, 5-ethynyl-, 5-Ethynyl-2,4(1H,3H)-pyrimidinedione, 5-Ethynyluracil, 5-ethynylpyrimidine-2,4(1H,3H)-dione, 776C85, Compound 776C, Gw776C85, NSC 687296, Unii-2E2W0W5Xiu

Descripción

Eniluracil is a prodrug of 5-fluorouracil, which is an anticancer drug. It is not active when taken orally and must be hydrolyzed by esterases in the stomach to produce 5-fluorouracil. The x-ray diffraction data for eniluracil was collected from untreated human serum samples. Eniluracil has been shown to have matrix effects on solid tumours in mice, leading to increased antitumor activity. This compound also inhibits the enzyme dihydropyrimidine dehydrogenase, which leads to decreased levels of diphosphate nucleotides and accumulation of dinucleotide phosphate. Enlargement of the tumor is also inhibited by this drug due to its ability to inhibit DNA replication and transcription.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 136.1 g/mol
• Fórmula: C₆H₄N₂O₂
• Pureza: Min. 95%
• Color/Forma: White Powder
• InChI: InChI=1S/CH4/h1H4
• Clave InChI: InChIKey=VNWKTOKETHGBQD-UHFFFAOYSA-N
• SMILES: C#Cc1c[nH]c(=O)[nH]c1=O