Información del producto
Nombre:Ethyl 4,6-dichloronicotinate
Marca:Biosynth
Descripción:Ethyl 4,6-dichloronicotinate (EDCN) is a hybrid drug that can be used as a clinical drug for the treatment of cancers. EDCN has been shown to have an antiproliferative effect in hematopoietic cells and tumor cells. It is also able to inhibit tyrosine kinase activity and cellular proliferation by inducing apoptosis. EDCN has been shown to be a potent inhibitor of cancer cell growth in vitro and in vivo, with IC50 values ranging from 1 to 10 μM. This drug is active against leukemia, lymphoma, breast cancer, prostate cancer, colorectal cancer, and other cancers that are sensitive to inhibition by tyrosine kinase inhibitors. EDCN binds reversibly to DNA with high affinity and specificity through hydrogen bonding interactions between the nucleobases on its aromatic ring system and the purine bases on dsDNA. This binding inhibits transcription by blocking access of RNA polymerase II to DNA templates
Aviso:Nuestros productos están destinados únicamente para uso en laboratorio. Para cualquier otro uso, por favor contáctenos.
Propiedades químicas
Peso molecular:220.05 g/mol
Fórmula:C8H7Cl2NO2
Pureza:Min. 95%
InChI:InChI=1S/C8H7Cl2NO2/c1-2-13-8(12)5-4-11-7(10)3-6(5)9/h3-4H,2H2,1H3
Clave InChI:InChIKey=AAUBVINEXCCXOK-UHFFFAOYSA-N
SMILES:CCOC(=O)c1cnc(Cl)cc1Cl
Consulta técnica sobre: Ethyl 4,6-dichloronicotinate
Use el carrito para solicitar presupuestos o pedidos
Si desea solicitar un presupuesto o realizar un pedido, por favor añada los productos deseados a su carrito y solicite un presupuesto o pedido desde el carrito. Es más rápido, más barato, y podrá beneficiarse de los descuentos y las ventajas disponibles.