4-Fluorophenylacetyl chloride
CAS: 459-04-1
Ref. 3D-FF35010
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Información del producto
- Benzeneacetyl chloride, 4-fluoro-
- 4-Fluorobenzeneacetyl chloride
- (p-Fluorophenyl)acetyl chloride
- Acetyl chloride, (p-fluorophenyl)-
4-Fluorophenylacetyl chloride is a potent inhibitor of the mineralocorticoid receptor and progesterone receptor, which are proteins expressed in the cell membrane. 4-Fluorophenylacetyl chloride has been shown to be effective against cancer cells in vivo, as well as inhibiting tumor necrosis factor-α (TNF-α) production induced by lipopolysaccharide (LPS) in vitro. This compound is a synthetic amide that binds to the steroid hormone receptors, preventing them from binding to their natural ligand. In addition, it inhibits the transcription of TNF-α genes by blocking the formation of DNA complexes with the protein nuclear factor κB (NFκB).
Propiedades químicas
Consulta técnica sobre: 3D-FF35010 4-Fluorophenylacetyl chloride
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