Fmoc-L-norvaline

CAS: 135112-28-6

Ref. 3D-FF47521

Información del producto

• Nombre: Fmoc-L-norvaline
• Sinónimos: Fmoc-L-Nva-OHFmoc-L-2-aminovaleric acidN-a-Fmoc-L-2-aminopentanoic acid, Fmoc-Nva-OH, Fmoc-Norvaline

Descripción

Fmoc-L-norvaline is a potent inhibitor of protein-protein interactions. It was originally identified as a cyclotide and has been shown to inhibit the serine protease activity of trypsin, chymotrypsin, and elastase. Fmoc-L-norvaline is also an analog of rauwolscine, which is used in the treatment of chronic hepatitis. The selectivity profile of Fmoc-L-norvaline is similar to that of rauwolscine, but with a higher potency against serine proteases. This molecule has been shown to have second order rate constants (k) in the range of 2×10 M−1s−1 to 1×10 M−1s−1 when bound to various proteins.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 339.39 g/mol
• Fórmula: C₂₀H₂₁NO₄
• Pureza: Min. 95%
• Color/Forma: White To Off-White Solid
• InChI: InChI=1S/C20H21NO4/c1-2-7-18(19(22)23)21-20(24)25-12-17-15-10-5-3-8-13(15)14-9-4-6-11-16(14)17/h3-6,8-11,17-18H,2,7,12H2,1H3,(H,21,24)(H,22,23)/t18-/m0/s1
• Clave InChI: InChIKey=JBIJSEUVWWLFGV-SFHVURJKSA-N
• SMILES: CCC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O