Fmoc-3-(2'-quinoyl)-L-alanine

CAS: 214852-56-9

Ref. 3D-FF47787

Información del producto

• Nombre: Fmoc-3-(2'-quinoyl)-L-alanine
• Sinónimos: Fmoc-L-Ala(2'-quinolyl)-OHFmoc-(S)-2-Amino-3-quinolin-2-yl-propionic acid, (2S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-quinolin-2-ylpropanoic acid, (αS)-α-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-quinolinepropanoic acid, 2-Quinolinepropanoic acid, α-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (αS)-, Fmoc-L-2-Quinoylalanine, Fmoc-Beta-(2-Quinolyl)-Ala-Oh

Descripción

Fmoc-3-(2'-quinoyl)-L-alanine is a hydrophobic amino acid that belongs to the group of cyclopentyl amino acids. It is synthesized from the coupling of l-phenylalanine and trifluoroacetic acid chloride in a cross-coupling reaction with pentafluorophenylchloride (PFPC). This process produces Fmoc-3-(2'-quinoyl)-L-alanine as an amorphous solid. The synthesis starts with the chemical ligation of two pieces of polystyrene, one bearing the desired sequence and the other bearing a protected l-phenylalanine. These are then combined in an activator solution containing PFPC, which causes cross-coupling to occur between the two pieces, leading to the desired product. The Fmoc group protects against unwanted side reactions during subsequent manipulations, but it can be removed by treatment with trifluoro

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 438.47 g/mol
• Fórmula: C₂₇H₂₂N₂O₄
• Pureza: Min. 95%
• InChI: InChI=1S/C27H22N2O4/c30-26(31)25(15-18-14-13-17-7-1-6-12-24(17)28-18)29-27(32)33-16-23-21-10-4-2-8-19(21)20-9-3-5-11-22(20)23/h1-14,23,25H,15-16H2,(H,29,32)(H,30,31)/t25-/m0/s1
• Clave InChI: InChIKey=IDOMHXAHHXHYMO-VWLOTQADSA-N
• SMILES: O=C(N[C@@H](Cc1ccc2ccccc2n1)C(=O)O)OCC1c2ccccc2-c2ccccc21