Fmoc-2-fluoro-D-phenylalanine

CAS: 198545-46-9

Ref. 3D-FF48030

Información del producto

• Nombre: Fmoc-2-fluoro-D-phenylalanine
• Sinónimos: Fmoc-D-Phe(2-F)-OHFmoc-o-fluoro-D-Phe-OH(R)-Fmoc-2-amino-3-(2-fluorophenyl)propionic acid, N-(9-Fluorenylmethoxycarbonyl)-2-fluorophenyl-D-alanine, Fmoc-D-Phe(2-F)-OH, Fmoc-D-2-Fluorophe, D-2-Fluorophenylalanine, FMOC protected, Fmoc-D-2-Fluorophenylalanine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-2-fluoro-L-phenylalanine, (2R)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-3-(2-fluorophenyl)propanoate, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-2-fluoro-D-phenylalanine, Fmoc-2-Fluoro-D-phenylalanine

Descripción

Fmoc-2-fluoro-D-phenylalanine is a ligand that blocks angiopoietin and inhibits angiogenesis. It also inhibits the signal transduction pathways of the receptor tyrosine kinase, which can lead to tumor regression. Fmoc-2-fluoro-D-phenylalanine is used in the screening of potential anticancer drugs that target angiogenesis. This drug has been shown to inhibit the growth of cancer cells in culture by blocking the expression of vascular endothelial growth factor (VEGF) and other proangiogenic factors.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 405.42 g/mol
• Fórmula: C₂₄H₂₀FNO₄
• Pureza: Min. 95%
• InChI: InChI=1S/C24H20FNO4/c25-21-12-6-1-7-15(21)13-22(23(27)28)26-24(29)30-14-20-18-10-4-2-8-16(18)17-9-3-5-11-19(17)20/h1-12,20,22H,13-14H2,(H,26,29)(H,27,28)/t22-/m1/s1
• Clave InChI: InChIKey=ARHOAMSIDCQWEW-JOCHJYFZSA-N
• SMILES: O=C(N[C@H](Cc1ccccc1F)C(=O)O)OCC1c2ccccc2-c2ccccc21