α-(4-Fluorophenyl)-4-(5-Fluoro-2-Pyrimidinyl)-1-Piperazi

CAS: 105565-56-8

Ref. 3D-FF98962

Información del producto

• Nombre: α-(4-Fluorophenyl)-4-(5-Fluoro-2-Pyrimidinyl)-1-Piperazi
• Sinónimos: ( -)-Bms 14802, 1-(4-Fluorophenyl)-4-[4-(5-Fluoropyrimidin-2-Yl)Piperazin-1-Yl]Butan-1-Ol, 1-Piperazinebutanol, alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-, 1-Piperazinebutanol, α-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-, Bms 181100, Bmy 14802, α-(4-Fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazinebutanol

Descripción

Alpha-(4-Fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazin (alphaFPP) is a potent and selective 5HT2A receptor antagonist. It blocks the binding of serotonin to these receptors, thereby preventing the activation of downstream signalling pathways and neurotransmitter release. AlphaFPP has been shown to have antipsychotic effects in animal models and may be useful for the treatment of schizophrenia. AlphaFPP also has neuroprotective effects against neuronal death induced by sodium carbonate, which may be due to its inhibition of dopamine and gamma-aminobutyric acid (GABA) receptors.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 348.39 g/mol
• Fórmula: C₁₈H₂₂F₂N₄O
• Pureza: Min. 95%
• InChI: InChI=1S/C18H22F2N4O/c19-15-5-3-14(4-6-15)17(25)2-1-7-23-8-10-24(11-9-23)18-21-12-16(20)13-22-18/h3-6,12-13,17,25H,1-2,7-11H2
• Clave InChI: InChIKey=ZXUYYZPJUGQHLQ-UHFFFAOYSA-N
• SMILES: OC(CCCN1CCN(c2ncc(F)cn2)CC1)c1ccc(F)cc1