Glucagon (19-29) (human, rat, porcine) trifluoroacetate salt

CAS: 64790-15-4

Ref. 3D-FG108770

Información del producto

• Nombre: Glucagon (19-29) (human, rat, porcine) trifluoroacetate salt
• Sinónimos: H-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-OH H-AQDFVQWLMNT-OH, H-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-OH, L-alanyl-L-glutaminyl-L-alpha-aspartyl-L-phenylalanyl-L-valyl-L-glutaminyl-L-tryptophyl-L-leucyl-L-methionyl-L-asparaginyl-L-threonine

Descripción

Glucagon is a peptide hormone that belongs to the group of vasoactive intestinal peptides. It is produced by the alpha cells of the pancreas and stimulates gluconeogenesis in the liver, thereby increasing blood glucose levels. Glucagon has also been shown to cause membrane hyperpolarization and cell death in cancer cells. Glucagon is a homologous protein that has been shown to have physiological effects similar to those of insulin, such as increased levels of cytosolic Ca2+ ions and camp levels. Glucagon binds to its receptor on the plasma membrane with high affinity, activating adenylate cyclase and phospholipase C, which leads to an increase in intracellular camp levels. This results in activation of protein kinase A (PKA), which phosphorylates proteins involved in glycogenolysis, glycolysis, and lipolysis. Glucagon also activates mitogen-activated protein kinases (MAPK

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 1,352.52 g/mol
• Fórmula: C₆₁H₈₉N₁₅O₁₈S
• Pureza: Min. 95%