H-Gly-Met-Gly-OH

CAS: 51529-34-1

Ref. 3D-FG109044

Información del producto

• Nombre: H-Gly-Met-Gly-OH
• Sinónimos: Glycine, N-(N-glycyl-L-methionyl)-, Glycylmethionylglycine, 4-(Glycylamino)-6-(Methylsulfanyl)-3-Oxonorleucine, {[N-(ammonioacetyl)-L-methionyl]amino}acetate

Descripción

H-Gly-Met-Gly-OH is an amide containing a sulfoxide group. It is synthesized from the amino acid glycine and the tripeptide Met-Gly-Gly. The synthesis of HMG was first reported by Sato in 1907, although it was not used as a drug until 1983. This drug has potential antitumor activity and inhibits the growth of certain tumor cells. HMG is metabolized by peptidases, which hydrolyze the peptide bond between glycine and Met-Gly-Gly. Hydrolysis of HMG yields glyoxylic acid (H2O2) and the amino acids glycine and methanol. HMG also inhibits the uptake of glucose into cells, which may be related to its antitumor effect. X-ray diffraction studies have shown that HMG has a carboxylate group at C6 that binds to three oxygen atoms, which are present in two

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 263.32 g/mol
• Fórmula: C₉H₁₇N₃O₄S
• Pureza: Min. 95%