3D-FG165277 - b-d-galactopyranosyl-fluoride

Lactosyl fluoride is a kinetic inhibitor of glycosidase enzymes. It has been shown to be an effective inhibitor of the enzyme β-galactosidase in both the presence and absence of calcium. Lactosyl fluoride has also been shown to inhibit other glycosidases, including α-galactosidase and α-mannosidase. The lactose derivative is activated by hydrogen fluoride, which allows it to react with the enzyme and block its activity. This product can be used as a chemical biology tool for studying glycoconjugates or as a medicine for treating diseases caused by the accumulation of oligosaccharides, such as Gaucher's disease or Tay-Sachs disease.

2,3,6,2',3',4',6'-Hepta-O-acetyl-a-D-lactosyl fluoride (HAP) is a synthetic compound that has been modified with fluorine and methyl groups. It is a monosaccharide with a glycosylation pattern that includes a terminal glucose unit. HAP has been shown to be an effective carbohydrate in the synthesis of complex carbohydrate structures.

4-Methoxyphenyl 2,3,6-tri-O-benzyl-4-O-(2,3-di-O-benzyl-b-D-galactopyranosyl)-b-D-glucopyranoside is a synthetic carbohydrate. It is made up of a saccharide and a sugar. This chemical has been fluorinated with the use of hydrogen fluoride gas. The chemical also has methyl groups that have been added to it. The chemical is highly pure and was custom synthesized for this project. This chemical can be used in glycosylation or click chemistry.