Guanfacine HCl
CAS:
Ref. 3D-FG33962
Información del producto
Nombre:Guanfacine HCl
Marca:Biosynth
Descripción:Guanfacine is a centrally acting alpha-2 adrenergic agonist that is used in the treatment of hypertension and attention deficit hyperactivity disorder (ADHD). It is a racemic mixture of two enantiomers, (+) and (-) guanfacine. Guanfacine acts on central alpha-2 receptors to reduce sympathetic outflow from the vasomotor center, which leads to reduced peripheral vascular resistance, decreased blood pressure, and increased heart rate. It also has been shown to increase the release of gamma-aminobutyric acid (GABA), a neurotransmitter that inhibits neuronal activity. Guanfacine is metabolized by CYP3A4 and CYP2D6 enzymes with elimination half-life of 10 hours. The drug has minimal drug interactions due to its low protein binding properties. Guanfacine has been found to be safe for use in humans at doses up to 3 mg/kg/day
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Propiedades químicas
Peso molecular:282.55 g/mol
Fórmula:C9H9Cl2N3O·HCl
Pureza:Min. 95%