4'-Hydroxy nimesulide
CAS: 109032-22-6
Ref. 3D-FH24067
1mg | Descatalogado | ||
2mg | Descatalogado | ||
5mg | Descatalogado | ||
10mg | Descatalogado |
Información del producto
- N-[2-(4-Hydroxyphenoxy)-4-nitrophenyl]methanesulfonamide4-Hydroxynimesulide
- N-[2-(4-Hydroxyphenoxy)-4-nitrophenyl]-methanesulfonamide
- 4-Nitro-2-(4'-Hydroxyphenoxy)Methanesulfonanilide
4'-Hydroxy nimesulide is a reactive metabolite of nimesulide. It is formed by the oxidation of nimesulide and other reactive metabolites, such as 4-hydroxynimesulide and 5-hydroxynimesulide. This metabolite can be detected in urine samples using a spectrophotometric method. The light emission from this metabolite is proportional to the concentration of the drug in urine. The 4'-hydroxy nimesulide has been found to have a matrix effect on clinical studies because it can interfere with the determination of nimesulide in human serum samples. It has also been shown to have an inhibitory effect on monocytes.