20a-Hydroxy prednisolone

CAS: 2299-46-9

Ref. 3D-FH24097

Información del producto

• Nombre: 20a-Hydroxy prednisolone
• Sinónimos: 20b-Dihydroprednisolone11b,17,20a,21-Tetrahydroxy-pregna-1,4-dien-3-one(11b,20S)-11,17,20,21-Tetrahydroxy-pregna-1,4-dien-3-one

Descripción

20a-Hydroxy prednisolone is an impurity that is found in the ophthalmic drug prednisolone. It has been shown to affect the perfusion of tissues in a rat's eye and can be used to validate analytical methods for quantifying prednisolone. The chromatographic method developed by Agilent was validated using tissue culture and reversed-phase chromatography, with excellent recoveries and reproducibility. The validation process also detected other impurities that were present at low levels (1%) such as 20-hydroxy-prednisolone, 17alpha-hydroxy-prednisolone, 18a-hydroxy-prednisolone, 19a-hydroxy-prednisolone, 21a-hydroxy-prednisolone, and 22a-hydroxy-prednisolone.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 362.46 g/mol
• Fórmula: C₂₁H₃₀O₅
• Pureza: Min. 95%
• Color/Forma: Powder