Información del producto
Nombre:3''-Hydroxy simvastatin
Sinónimos:
- 3-Hydroxy-2,2-dimethylbutanoic acid 1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naph thalenyl ester
Marca:Biosynth
Descripción:3''-Hydroxy simvastatin is a potent and selective inhibitor of HMG-CoA reductase, the enzyme that catalyzes the conversion of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) to mevalonate in the cholesterol biosynthetic pathway. It inhibits the production of cholesterol and other steroids, including glucocorticoids, mineralocorticoids, and sex hormones. 3''-Hydroxy simvastatin is used to lower blood cholesterol levels in patients with hypercholesterolemia. The acid form of 3''-hydroxy simvastatin is detectable by fluorescent probes in biological fluids at concentrations as low as 1 nanomolar. The lactone form of 3''-hydroxy simvastatin has been shown to have similar potency as atorvastatin.
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Propiedades químicas
Peso molecular:434.57 g/mol
Fórmula:C25H38O6
Pureza:Min. 95%
Color/Forma:White Slightly Yellow Powder