Información del producto
Nombre:rac 8-Hydroxy efavirenz
Sinónimos:
- 6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one8-Hydroxyefavirenz
Marca:Biosynth
Descripción:Efavirenz is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used in the treatment of HIV. It has been shown to be reactive with sodium carbonate, forming a stable complex that can be measured by LC-MS/MS. The formation rate of this complex may be influenced by the presence of other drugs, such as rifampin, which inhibits cytochrome P450 activity and reduces efavirenz metabolism. This drug has been shown to inhibit human Cytochrome P450 3A4 (CYP3A4) and may have increased plasma concentrations when administered with CYP3A4 inhibitors such as ketoconazole or erythromycin. Efavirenz is also metabolized in the liver by cytochrome P450 enzymes, mainly CYP3A4. Pharmacokinetic modeling has been used to study the drug's effects on hepatic clearance and plasma concentrations in humans.
Aviso:Nuestros productos están destinados únicamente para uso en laboratorio. Para cualquier otro uso, por favor contáctenos.
Propiedades químicas
Peso molecular:331.67 g/mol
Fórmula:C14H9ClF3NO3
Pureza:Min. 95%
Color/Forma:White Powder
SMILES:O=C1Nc2c(O)cc(Cl)cc2C(C#CC2CC2)(C(F)(F)F)O1
Consulta técnica sobre: rac 8-Hydroxy efavirenz
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