N-Hydroxy-5-norbornene-2,3-dicarboximide

CAS: 21715-90-2

Ref. 3D-FH31434

Información del producto

• Nombre: N-Hydroxy-5-norbornene-2,3-dicarboximide
• Sinónimos: HONBN-Hydroxybicyclo[2.2.1]hept-5-ene-2,3-dicarboxylic acid imideN-Hydroxy-5-norbornene-2,3-dicarboxylic acid imide, (3aR,4S,7R,7aS)-2-hydroxy-3a,4,7,7a-tetrahydro-1H-4,7-methanoisoindole-1,3(2H)-dione, (3aR,4S,7S,7aR)-2-hydroxy-3a,4,7,7a-tetrahydro-1H-4,7-methanoisoindole-1,3(2H)-dione, 2-hydroxy-3a,4,7,7a-tetrahydro-1H-4,7-methanoisoindole-1,3(2H)-dione, 3,5-Dioxo-4-azatricyclo[5.2.1.0²′⁶]dec-8-en-4-ol, 3a,4,7,7a-Tetrahydro-2-hydroxy-4,7-methano-1H-isoindole-1,3(2H)-dione, 4,7-Methano-1H-isoindole-1,3(2H)-dione, 3a,4,7,7a-tetrahydro-2-hydroxy-, 5-Norbornene-2,3-dicarboximide, N-hydroxy-, Honb, N-Hydroxy-5-bicyclo[2.2.1]heptene-2,3-dicarboximide, N-Hydroxy-5-norbornene-endo-2,3-dicarboximide, N-Hydroxybicyclo[2.2.1]hept-5-ene-2,3-dicarboximide, N-hydroxy-5-norbornene-2.3-dicarboxylimide, NSC 100740, NSC 12953, endo-N-Hydroxy-5-norbornene-2,3-dicarboximide

Descripción

N-Hydroxy-5-norbornene-2,3-dicarboximide (NHD) is a compound that has antiviral activity and is used to treat HIV infections. It inhibits the reverse transcriptase enzyme in the virus, which blocks the synthesis of viral DNA. The ferroelectric properties of NHD were first observed by observing changes in its melting point when mixed with water. This property makes it useful for diagnosis purposes. In animal studies, a dose of 5 mg/kg was found to be effective against cancer cells and the drug showed no toxicity in humans at doses up to 500 mg/day. The optimal reaction conditions for NHD are pH 6 and temperature 45 degrees Celsius.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 179.17 g/mol
• Fórmula: C₉H₉NO₃
• Pureza: Min. 98 Area-%
• Color/Forma: White Powder
• InChI: InChI=1S/C9H9NO3/c11-8-6-4-1-2-5(3-4)7(6)9(12)10(8)13/h1-2,4-7,13H,3H2
• Clave InChI: InChIKey=ZUSSTQCWRDLYJA-UHFFFAOYSA-N
• SMILES: O=C1C2C3C=CC(C3)C2C(=O)N1O