2-Hydroxy-4-(trifluoromethyl)benzaldehyde

CAS: 58914-34-4

Ref. 3D-FH63505

Información del producto

• Nombre: 2-Hydroxy-4-(trifluoromethyl)benzaldehyde
• Sinónimos: 4-Trifluoromethylsalicyaldehyde

Descripción

2-Hydroxy-4-(trifluoromethyl)benzaldehyde is an analgesic and anti-inflammatory agent that belongs to the pyrazole family. It has shown analgesic and anti-inflammatory effects in animal studies. 2-Hydroxy-4-(trifluoromethyl)benzaldehyde has been shown to be a potent inhibitor of cyclooxygenase (COX), which is responsible for prostaglandin synthesis, and as such, may have potential as a treatment for inflammatory conditions such as rheumatoid arthritis. This drug also inhibits the production of nitric oxide, which is involved in vasodilation and increased blood flow. 2-Hydroxy-4-(trifluoromethyl)benzaldehyde has been demonstrated to inhibit COX enzymes by forming a covalent bond with active site serine residues on the enzyme. The docked complex shows hydrogen bonding interactions between the hydroxyl group of 2

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 190.12 g/mol
• Fórmula: C₈H₅F₃O₂
• Pureza: Min. 95%
• InChI: InChI=1S/C8H5F3O2/c9-8(10,11)6-2-1-5(4-12)7(13)3-6/h1-4,13H
• Clave InChI: InChIKey=YHYNJGHMBMXAFB-UHFFFAOYSA-N
• SMILES: O=Cc1ccc(C(F)(F)F)cc1O