AM 630

CAS: 164178-33-0

Ref. 3D-FI156054

Información del producto

• Nombre: AM 630
• Sinónimos: (6-Iodo-2-methyl-1-(2-morpholinoethyl)-1H-indol-3-yl)(4-methoxyphenyl)methanone, 6-Iodo-2-Methyl-1-[[2-(4-Morpholinyl)Ethyl]-1H-Indol-3-Yl](4-Methoxyphenyl)Methanone, Am630, Iodopravadoline, Methanone, [6-iodo-2-methyl-1-[2-(4-morpholinyl)ethyl]-1H-indol-3-yl](4-methoxyphenyl)-, [6-Iodo-2-methyl-1-(2-morpholin-4-ylethyl)indol-3-yl]-(4-methoxyphenyl)methanone, [6-iodo-2-methyl-1-(2-morpholin-4-ylethyl)-1H-indol-3-yl](4-methoxyphenyl)methanone

Descripción

AM630 is an aminoalkylindole synthetic cannabinoid which acts as a potent selective inverse agonist at the cannabinoid receptor CB2 (Ki = 32.1 nM) and a partial agonist at cannabinoid receptor CB1. However, it has also been reported to act as an antagonist at the CB1 receptor at higher concentrations2. In vitro, AM630 showed anti-tumorigenic properties by decreased viability in a prostate adenocarcinoma cell line and reducing pro-inflammatory cytokines in vitro as well as in vivo2,3. It also has been shown to activate TRPA1 channels in neural cultures as well as stimulate TRPA1-mediated antihyperalgesia in wild-type mice and rats4.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 504.36 g/mol
• Fórmula: C₂₃H₂₅IN₂O₃
• Pureza: Min. 95%
• Color/Forma: Powder