Irgarol

CAS: 28159-98-0

Ref. 3D-FI24649

Información del producto

• Nombre: Irgarol
• Sinónimos: N-Cyclopropyl-N'-(1,1-dimethylethyl)-6-(methylthio)-1,3,5-triazine-2,4-diamine2-(tert-Butylamino)-4-(cyclopropylamino)-6-(methylthi o)-s-triazine, 1,3,5-Triazine-2,4-diamine, N-cyclopropyl-N′-(1,1-dimethylethyl)-6-(methylthio)-, 1,3,5-Triazine-2,4-diamine, N²-cyclopropyl-N⁴-(1,1-dimethylethyl)-6-(methylthio)-, 2 N'-tert-butyl-N-cyclopropyl-6-(methylthio)-1,3,5-triazine-2,4-diamine, 2-(Methylthio)-4-(tert-butylamino)-6-(cyclopropylamino)-s-triazine, 2-(Tret-butylamino)-4-cyclopropylamino-6-methylthio-s-triazine, 2-(tert-Butylamino)-4-(cyclopropylamino)-6-(methylthio)-1,3,5-triazine, 2-(tert-Butylamino)-4-(cyclopropylamino)-6-(methylthio)-s-triazine, 2-Methylthio-4-t-butylamino-6-cyclopropylamino-s-triazine, 2-Methylthio-4-tert-butylamino-6-cyclopropylamino-[1,3,5]triazine, 2-N-tert-Butyl-4-N-cyclopropyl-6-methylsulfanyl-1,3,5-triazine-2,4-diamine, Cybutrin, Cybutryne, Dp 2159, Irgaguard A 2000, Irgaguard D 1071, Irgarol 1051, Irgarol 1071, Microban Additive IA 1, N-Cyclopropyl-N′-(1,1-dimethylethyl)-6-(methylthio)-1,3,5-triazine-2,4-diamine, N-tert-butyl-N'-cyclopropyl-6-(methylsulfanyl)-1,3,5-triazine-2,4-diamine, N²-Cyclopropyl-N⁴-(1,1-dimethylethyl)-6-(methylthio)-1,3,5-triazine-2,4-diamine, Nuocide 1051, SanAlga 1907, s-Triazine, 2-(tert-butylamino)-4-(cyclopropylamino)-6-(methylthio)-, 1,3,5-Triazine-2,4-diamine, N2-cyclopropyl-N4-(1,1-dimethylethyl)-6-(methylthio)-, N2-Cyclopropyl-N4-(1,1-dimethylethyl)-6-(methylthio)-1,3,5-triazine-2,4-diamine

Descripción

Irgarol is a cell cycle inhibitor that inhibits the activity of cyclin-dependent kinase (CDK) to induce apoptosis in tumor cells. Irgarol is a carboxylic acid with a high affinity for the hydrophobic region of CDK, which prevents the enzyme from phosphorylating its substrates. This results in cell death by preventing cells from completing their normal cell cycle and inducing apoptosis. Irgarol has been shown to inhibit growth and induce apoptosis in hepg2 cells, an immortalized human hepatocyte cell line, as well as in other tumor cells.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 253.37 g/mol
• Fórmula: C₁₁H₁₉N₅S
• Pureza: Min. 95%
• InChI: InChI=1S/C11H19N5S/c1-11(2,3)16-9-13-8(12-7-5-6-7)14-10(15-9)17-4/h7H,5-6H2,1-4H3,(H2,12,13,14,15,16)
• Clave InChI: InChIKey=HDHLIWCXDDZUFH-UHFFFAOYSA-N
• SMILES: CSc1nc(NC2CC2)nc(NC(C)(C)C)n1