Kenpaullone

CAS: 142273-20-9

Ref. 3D-FK24755

Información del producto

• Nombre: Kenpaullone
• Sinónimos: 9-Bromo-7,12-dihydro-indolo[3,2-d][1]-benzazepin-6(5H)-one9-Bromopaullone, 8-Bromo-7,12-Dihydro-Indolo[3,2-D][1]-Benzazepin-6(5H)-One, 9-Bromo-7,12-Dihydro-Indolo[3,2-D][1]Benzazepin-6(5H)-One, 9-Bromo-7,12-dihydro-indolo[3,2-d][1]benzazepin-6(5H)-one, NSC 664704, 9-Bromo-7,12-dihydroindolo[3,2-d][1]benzazepin-6(5H)-one, 9-Bromopaullone, Indolo[3,2-d][1]benzazepin-6(5H)-one, 9-bromo-7,12-dihydro-, Nsc-664704
• CAS: 142273-20-9

Descripción

Inhibitor of glycogen synthase 3 (GSK-3) and cyclin-dependent kinases CDK1, CDK2 and CDK5. Kenpaullone can substitute transcription factor Klf4 in reprogramming of fibroblast to induced pluripotent stem cells when using the method of ectopic expression of transcriptional factors. In an in vitro model for Alzheimer’s disease, kenpaullone decreased production of amyloid beta peptides Aβ40 and Aβ42.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 326.00548
• Fórmula: C₁₆H₁₁BrN₂O
• Pureza: Min. 95%
• Color/Forma: Yellow To Dark Yellow Solid
• InChI: InChI=1S/C16H11BrN2O/c17-9-5-6-14-11(7-9)12-8-15(20)18-13-4-2-1-3-10(13)16(12)19-14/h1-7,19H,8H2,(H,18,20)
• Clave InChI: InChIKey=QQUXFYAWXPMDOE-UHFFFAOYSA-N
• SMILES: O=C1Cc2c([nH]c3ccc(Br)cc23)-c2ccccc2N1