Información del producto
Nombre:Lactoferricin B25
Sinónimos:
- LFcinB 25
- Lactoferricin B (17-41) (bovine)H-Phe-Lys-Cys-Arg-Arg-Trp-Gln-Trp-Arg-Met-Lys-Lys-Leu-Gly-Ala-Pro-Ser-Ile-Thr-Cys-Val-Ar g-Arg-Ala-Phe-OH trifluoroacetate salt (Disulfide bond)
Marca:Biosynth
Descripción:Lactoferricin B25 is a potent anticancer agent that has shown significant activity in vitro against cancer cell lines. It has been shown to induce apoptosis and autophagy, which are both methods of inducing cell death. Lactoferricin B25 also induces caspase-mediated apoptosis and has been shown to be effective in the treatment of cancer cells in vivo. Lactoferricin B25 binds with high affinity to the cell membrane, which is thought to be responsible for its anticancer activity. The half-maximal inhibitory concentration (IC50) for this compound is about 2 μM, with a concomitant cytotoxic effect at 10 μM. Lactoferricin B25 binds to DNA polymerase, preventing DNA replication and transcription. The binding of lactoferricin B25 to DNA polymerase inhibits the synthesis of RNA from DNA templates by inhibiting the elongation step of transcription.
Aviso:Nuestros productos están destinados únicamente para uso en laboratorio. Para cualquier otro uso, por favor contáctenos.
Propiedades químicas
Peso molecular:3,123.78 g/mol
Fórmula:C141H224N46O29S3
Pureza:Min. 90 Area-%
Color/Forma:Powder
Consulta técnica sobre: Lactoferricin B25
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