Lapatinib ditosylate monohydrate
CAS: 388082-78-8
Ref. 3D-FL24843
| 1g | A consultar | |
| 2g | A consultar | |
| 5g | A consultar | |
| 10g | A consultar | |
| 25g | A consultar |
Información del producto
- N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-4-quinazolinamine bis(4-meth ylbenzenesulfonate) ditosylateGW-572016F ditosylateTykerb ditosylate
Inhibitor of EGFR (ErbB1) and HER2 (ErbB2) receptor tyrosine kinases. Used for sensitization of HER2-overexpressing cancer cells to radiation as well as chemotherapy to tamoxifen- and trastuzumab-resistant cell lines. The compound blocks signalling via Akt and mitogen-activated protein kinase (MAPK) pathways leading to reduced cell survival. In trastuzumab resistant cancer cells, it inhibits HER2 phosphorylation, prevents receptor ubiquitination and causes accumulation of inactive HER2 dimers on the cell surface.
Propiedades químicas
Consulta técnica sobre: 3D-FL24843 Lapatinib ditosylate monohydrate
Si desea solicitar un presupuesto o realizar un pedido, por favor añada los productos deseados a su carrito y solicite un presupuesto o pedido desde el carrito. Es más rápido, más barato, y podrá beneficiarse de los descuentos y las ventajas disponibles.
