Información del producto
Nombre:
Lasofoxifene
Sinónimos:
- (5R,6S)-5,6,7,8-Tetrahydro-6-phenyl-5-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-2-naphthalenol
- (-)-cis-6(S)-Phenyl-5(R)-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-5,6,7,8-tetrahydronaphthalen-2-ol
- (5R,6S)-6-phenyl-5-[4-(2-pyrrolidin-1-ylethoxy)phenyl]tetralin-2-ol
- (5R,6S)-6-phenyl-5-{4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}-5,6,7,8-tetrahydronaphthalen-2-ol
- (5R-cis)-5,6,7,8-Tetrahydro-6-phenyl-5-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-2-naphthalenol
- 2-Naphthalenol, 5,6,7,8-tetrahydro-6-phenyl-5-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-, (5R,6S)-
- 2-Naphthalenol, 5,6,7,8-tetrahydro-6-phenyl-5-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-, (5R-cis)-
- Cp-336,156
Descripción:
Lasofoxifene is a selective inhibitor of the cell cycle kinase, CDK4 and CDK6. The drug has been shown to inhibit the proliferation of cancer cells in vitro in human breast cancer cell lines. It also inhibits cell proliferation in vivo by inhibiting the proliferation of cancer cells that have been transplanted into mice. Lasofoxifene has also been shown to inhibit the growth of prostate cancer cells and may be useful for treating neurodegenerative disorders such as Alzheimer's disease.
Aviso:
Nuestros productos están destinados únicamente para uso en laboratorio. Para cualquier otro uso, por favor contáctenos.
Marca:
Biosynth
Almacenamiento de larga duración:
Notas:
Propiedades químicas
Peso molecular:
413.55 g/mol
Fórmula:
C28H31NO2
Pureza:
Min. 95%
InChI:
InChI=1S/C28H31NO2/c30-24-11-15-27-23(20-24)10-14-26(21-6-2-1-3-7-21)28(27)22-8-12-25(13-9-22)31-19-18-29-16-4-5-17-29/h1-3,6-9,11-13,15,20,26,28,30H,4-5,10,14,16-19H2/t26-,28+/m1/s1
Clave InChI:
InChIKey=GXESHMAMLJKROZ-IAPPQJPRSA-N
SMILES:
Oc1ccc2c(c1)CC[C@H](c1ccccc1)[C@@H]2c1ccc(OCCN2CCCC2)cc1
MDL:
Punto de fusión:
Punto de ebullición:
Punto de inflamabilidad:
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EINECS:
Merck:
Código HS:
