Lavendustin A

CAS: 125697-92-9

Ref. 3D-FL24861

Información del producto

• Nombre: Lavendustin A
• Sinónimos: 5-[[(2,5-Dihydroxyphenyl)methyl][(2-hydroxyphenyl)methyl]amino]-2-hydroxy-benzoic acidNSC 678027, 5-Amino-[(N-2,5-Dihydroxybenzyl)-N'-2-Hydroxybenzyl]Salicylic Acid, 5-[(2,5-Dihydroxybenzyl)(2-Hydroxybenzyl)Amino]-2-Hydroxybenzoate, 5-[(2,5-Dihydroxybenzyl)(2-Hydroxybenzyl)Amino]-2-Hydroxybenzoic Acid, 5-[[(2,5-Dihydroxyphenyl)Methyl][(2-Hydroxyphenyl)Methyl]Amino]-2-Hydroxybenzoic Acid, Benzoic acid, 5-[[(2,5-dihydroxyphenyl)methyl][(2-hydroxyphenyl)methyl]amino]-2-hydroxy-, NSC 678027, Rg14355

Descripción

Lavendustin A (LAVA) is a novel, potent and selective small molecule inhibitor of the bcr-abl kinase. It has been shown to inhibit the proliferation of human cells in vitro, including human leukemia cells, human lymphoma cells, and human breast carcinoma cells. Lavendustin A also inhibits HIV infection in vitro by blocking HIV-1 reverse transcriptase activity. The compound also promotes axonal growth in vivo and has neurotrophic effects on neurons in culture. This drug may be useful as a potential treatment for autoimmune diseases such as multiple sclerosis and rheumatoid arthritis.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 381.38 g/mol
• Fórmula: C₂₁H₁₉NO₆
• Pureza: Min. 95%
• InChI: InChI=1S/C21H19NO6/c23-16-6-8-19(25)14(9-16)12-22(11-13-3-1-2-4-18(13)24)15-5-7-20(26)17(10-15)21(27)28/h1-10,23-26H,11-12H2,(H,27,28)
• Clave InChI: InChIKey=ULTTYPMRMMDONC-UHFFFAOYSA-N
• SMILES: O=C(O)c1cc(N(Cc2ccccc2O)Cc2cc(O)ccc2O)ccc1O