Lovastatin hydroxy acid, sodium salt

CAS: 75225-50-2

Ref. 3D-FL24953

Información del producto

• Nombre: Lovastatin hydroxy acid, sodium salt
• Sinónimos: Lovastatin sodium saltMB 530BMevinolinic acid, 1-Naphthaleneheptanoic acid, 1,2,6,7,8,8a-hexahydro-β,δ-dihydroxy-2,6-dimethyl-8-(2-methyl-1-oxobutoxy)-, monosodium salt, [1S-[1α(βS*,δS*),2α,6β,8β(R*),8aα]]-, 1-Naphthaleneheptanoic acid, 1,2,6,7,8,8a-hexahydro-β,δ-dihydroxy-2,6-dimethyl-8-(2-methyl-1-oxobutoxy)-, sodium salt (1:1), (βR,δR,1S,2S,6R,8S,8aR)-, 1-Naphthaleneheptanoic acid, 1,2,6,7,8,8a-hexahydro-β,δ-dihydroxy-2,6-dimethyl-8-[(2S)-2-methyl-1-oxobutoxy]-, monosodium salt, (βR,δR,1S,2S,6R,8S,8aR)-, Lovastatin sodium salt, MSD 803, sodium salt, Mb 530B, Monacolin K sodium salt, Sodium mevinolinate, sodium (3R,5R)-7-[(1S,2S,6R,8S,8aR)-2,6-dimethyl-8-{[(2S)-2-methylbutanoyl]oxy}-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoate

Descripción

Lovastatin is a chemical species belonging to the chemical class of statins. It inhibits cholesterol synthesis by inhibiting the enzyme HMG-CoA reductase, which is involved in converting mevalonate to isoprene and farnesyl pyrophosphate. Lovastatin has been shown to be effective against a number of bacterial strains, including E. coli, Salmonella enterica serovar Typhimurium, and Helicobacter pylori. This drug has been shown to be active against HIV-1 and human papillomavirus (HPV), with potent inhibitory activity at low doses. Lovastatin also inhibits the production of neutrophil chemotactic protein 1 (PD-L1) in cells infected with human cytomegalovirus (HCMV). The major metabolite of lovastatin is pravastatin, which exhibits similar properties but weaker potency.END>

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 444.54 g/mol
• Fórmula: C₂₄H₃₇NaO₆
• Pureza: Min. 97 Area-%