6-Methyl-3,4-dihydronaphthalen-1(2H)-one
CAS: 51015-29-3
Ref. 3D-FM142292
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Información del producto
- 1(2H)-Naphthalenone, 3,4-dihydro-6-methyl-
- 3,4-Dihydro-6-methyl-1(2H)-naphthalenone
- 6-Methyl-1-tetralone
- 6-Methyl-α-tetralone
- 6-methyl-3,4-dihydronaphthalen-1(2H)-one
6-Methyl-3,4-dihydronaphthalen-1(2H)-one is a nonsteroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties. This compound is an analog of bexarotene, which is used as a cancer chemotherapeutic agent. 6-Methyl-3,4-dihydronaphthalen-1(2H)-one has been shown to inhibit lipid biosynthesis in the liver by interacting with the ligand binding domain of the peroxisome proliferator -activated receptor alpha (PPARα). The NSAID also inhibits the production of prostaglandins that are involved in inflammation and pain. 6-Methyl-3,4-dihydronaphthalen-1(2H)-one binds to PPARα in the ligand binding domain and prevents it from activating transcription.
Propiedades químicas
Consulta técnica sobre: 3D-FM142292 6-Methyl-3,4-dihydronaphthalen-1(2H)-one
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