[(1S,3S)-3-[[4-Methoxy-3-(3-methoxypropoxy)phenyl]methyl]-4-methyl-1-[(2S, 4S)-tetrahydro-4-(1-methylethyl)-5-oxo-2-furanyl]pentyl]c arbamic acid 1,1-tert-butyl ester

CAS: 866030-35-5

Ref. 3D-FM25237

Información del producto

• Nombre: [(1S,3S)-3-[[4-Methoxy-3-(3-methoxypropoxy)phenyl]methyl]-4-methyl-1-[(2S, 4S)-tetrahydro-4-(1-methylethyl)-5-oxo-2-furanyl]pentyl]c arbamic acid 1,1-tert-butyl ester
• Sinónimos: N-[(1S,3S)-3-[[4-Methoxy-3-(3-methoxypropoxy)phenyl]methyl]-4-methyl-1-[(2S, 4S)-tetrahydro-4-(1-methylethyl)-5-oxo-2-furanyl]pentyl ]carbamic acid 1,1-dimethylethyl ester, 1,1-Dimethylethyl N-[(1S,3S)-3-[[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl]-4-methyl-1-[(2S,4S)-tetrahydro-4-(1-methylethyl)-5-oxo-2-furanyl]pentyl]carbamate, 1,1-Dimethylethyl[(1S,3S)-3-[[4-methoxy-3-(3-methoxypropoxy)phenyl] methyl]-4-methyl-1-[((2S,4S)-tetrahydro-4-(1-methylethyl)-5-oxo-2-furanyl]pentyl]carbamic Acid 1,1-tert-Butyl Ester, Carbamic acid, N-[(1S,3S)-3-[[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl]-4-methyl-1-[(2S,4S)-tetrahydro-4-(1-methylethyl)-5-oxo-2-furanyl]pentyl]-, 1,1-dimethylethyl ester, Carbamic acid, [(1S,3S)-3-[[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl]-4-methyl-1- [(2S,4S)-tetrahydro-4-(1-methylethyl)-5-oxo-2-furanyl]pentyl]-, 1,1-dimethylethyl ester, [(1S,3S)-3-[[4-Methoxy-3-(3-methoxypropoxy)phenyl]methyl]-4-methyl-1-[(2S, 4S)-tetrahydro-4-(1-methylethyl)-5-oxo-2-furanyl]pentyl]carbamic Acid 1,1-tert-Butyl Ester, tert-Butyl(1S,3S)-1-((2S,4S)-4-isopropyl-5-oxotetrahydrofuran-2-yl)-3-(4-methoxy-3-(3-methoxypropoxy)benzyl)-4-methylpentylcarbamate

Descripción

[(1S,3S)-3-[[4-Methoxy-3-(3-methoxypropoxy)phenyl]methyl]-4-methyl-1-[(2S, 4S)-tetrahydro-4-(1-methylethyl)-5-oxo-2-furanyl]pentyl]car bamic acid 1,1-tert-butyl ester is a chiral building block that has been used in the scalable synthesis of various pharmaceuticals. The synthesis begins with ammonolysis of an amino chloride and chloroacetate. This reaction is followed by acetate extraction to yield the desired product. This process can be optimized by ring opening, magnesium removal and alkylation of aromatic hydrocarbons. The final reaction is the Suzuki coupling reaction with chromatographic purification.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 535.71 g/mol
• Fórmula: C₃₀H₄₉NO₇
• Pureza: Min. 95%