a-Me-Gly(Pentenyl)-OH
CAS: 1011309-61-7
Ref. 3D-FM72815
1g | A consultar | ||
50mg | A consultar | ||
100mg | A consultar | ||
250mg | A consultar | ||
500mg | A consultar |
Información del producto
- Alpha-Allyl-L-Ala
- (S)-Alpha-Methyl-Allylglycine
- -Allyl-L-Ala
- A-Allyl-L-Ala
- 3-Butenoicacid,2-amino-2-methyl-,(2S)-
- (2S)-2-ammonio-2-methylbut-3-enoate
- (S)-2-amino-2-methyl-4-pentenoicacid
- (2S)-2-Amino-2-methyl-3-butenoic acid
- (S)- 2-(5'-pentenyl) alanine
a-Me-Gly(Pentenyl)-OH is a small molecule that inactivates proteins by binding to their ATP binding site. a-Me-Gly(Pentenyl)-OH has been shown to inhibit cellular proliferation, with an IC50 of 2.5 μM, as well as cancer cell growth in vitro. The kinetics of the reaction have been characterized and it was found that the drug binds to wild-type p53 protein (the protein mutated in many human cancers) and inhibits its activity by modulating its conformation, preventing it from binding to DNA. This inhibition leads to decreased DNA synthesis and cell cycle arrest at the G1 phase. In addition, a-Me-Gly(Pentenyl)-OH has been shown to dephosphorylate phosphatases and stapling agents such as PP2A and PP4, which are involved in regulating cellular proliferation.
Propiedades químicas
Consulta técnica sobre: 3D-FM72815 a-Me-Gly(Pentenyl)-OH
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