4-Nitro-2,3-dihydro-1H-indole
CAS: 84807-26-1
Ref. 3D-FN52053
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Información del producto
- 4-Nitroindoline
4-Nitro-2,3-dihydro-1H-indole is a potent antagonist of the adrenergic receptor. It has minimal effects on other receptors and binding sites. This drug has been shown to be selective for the human alpha 1A and beta 2 adrenergic receptors in binding studies. 4-Nitro-2,3-dihydro-1H-indole antagonizes the effect of epinephrine on these receptors and attenuates their response to agonists such as phenylephrine. The oral bioavailability of this drug is optimized in animal studies using cyanoguanidine, which facilitates the conversion of 4-nitro-2,3-dihydro-1H-indole to its active form. This active form has an oral bioavailability of >90%.
Propiedades químicas
Consulta técnica sobre: 3D-FN52053 4-Nitro-2,3-dihydro-1H-indole
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