OP-1118

CAS: 1030825-28-5

Ref. 3D-FO71470

Información del producto

• Nombre: OP-1118
• Sinónimos: Fidaxomicin-Met

Descripción

OP-1118 is a small molecule that inhibits the activity of NF-κB, which is a major regulator of inflammatory responses. It has been shown to have an inhibitory effect on intestinal inflammation and infectious diseases. OP-1118 also has bactericidal properties and can be used in conjunction with antibiotics to treat bacterial infections. This drug is currently undergoing clinical development as a potential treatment for inflammatory bowel disease. Animal studies have shown that OP-1118 has little effect on the gut flora, which may be due to its low plasma concentrations.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 987.95 g/mol
• Fórmula: C₄₈H₆₈Cl₂O₁₇
• Pureza: Min. 95%
• Color/Forma: Powder
• InChI: InChI=1S/C48H68Cl2O17/c1-11-27-20-23(4)30(52)16-14-13-15-28(21-62-47-42(61-10)39(57)41(26(7)63-47)65-45(60)32-29(12-2)33(49)36(54)34(50)35(32)53)44(59)64-31(25(6)51)18-17-22(3)19-24(5)40(27)66-46-38(56)37(55)43(58)48(8,9)67-46/h13-15,17,19-20,25-27,30-31,37-43,46-47,51-58H,11-12,16,18,21H2,1-10H3/b14-13-,22-17+,23-20+,24-19-,28-15+/t25-,26+,27+,30+,31+,37-,38+,39-,40+,41+,42-,43+,46-,47+/m1/s1
• Clave InChI: InChIKey=MWZWKUKATWMWGS-TYEQEDGKSA-N
• SMILES: CCc1c(Cl)c(O)c(Cl)c(O)c1C(=O)O[C@H]1[C@H](C)O[C@H](OC/C2=C\C=C\C[C@H](O)/C(C)=C/[C@H](CC)[C@@H](O[C@@H]3OC(C)(C)[C@@H](O)[C@H](O)[C@@H]3O)/C(C)=C/C(C)=C/C[C@@H]([C@@H](C)O)OC2=O)[C@H](OC)[C@@H]1O