WAY 316606

CAS: 915759-45-4

Ref. 3D-FP101364

Información del producto

• Nombre: WAY 316606
• Sinónimos: 5-(Phenylsulfonyl)-N-(piperidin-4-yl)-2-(trifluoromethyl)benzenesulfonamide

Descripción

WAY 316606 is a potent, orally administered small molecule that inhibits the Wnt signaling pathway by blocking the action of β-catenin. It has been shown to have potential for treating eye disorders, including age-related macular degeneration. This drug also has potential for treatment of cell and nervous system diseases such as Alzheimer's disease and Huntington's disease. WAY 316606 inhibits the transcriptional activity of the β-catenin/Tcf4 complex by binding to it and preventing its translocation into the nucleus. In addition, WAY 316606 prevents downstream activation of genes regulated by β-catenin signaling, including c-myc and cyclin D1. This drug also blocks growth factor receptor tyrosine kinases and monoclonal antibodies that activate these receptors.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 448.48 g/mol
• Fórmula: C₁₈H₁₉F₃N₂O₄S₂
• Pureza: Min. 95%
• InChI: InChI=1S/C18H19F3N2O4S2/c19-18(20,21)16-7-6-15(28(24,25)14-4-2-1-3-5-14)12-17(16)29(26,27)23-13-8-10-22-11-9-13/h1-7,12-13,22-23H,8-11H2
• Clave InChI: InChIKey=ITBGJNVZJBVPLJ-UHFFFAOYSA-N
• SMILES: O=S(=O)(NC1CCNCC1)c1cc(S(=O)(=O)c2ccccc2)ccc1C(F)(F)F