Pradigastat
CAS: 956136-95-1
Ref. 3D-FP103386
| 1mg | Descatalogado | ||
| 2mg | Descatalogado | ||
| 5mg | Descatalogado | ||
| 10mg | Descatalogado | ||
| 25mg | Descatalogado |
Información del producto
Nombre:
Pradigastat
Sinónimos:
- Lcq 908Nxa
- trans-4-[4-[5-[[6-(Trifluoromethyl)-3-pyridinyl]amino]-2-pyridinyl]phenyl]cyclohexaneacetic acid
Descripción:
Pradigastat is a small molecule that inhibits the activity of diacylglycerol acyltransferase-2 (DGAT-2) and hepatic lipase. It is used to treat patients with high levels of low-density lipoprotein cholesterol (LDL-C). Pradigastat binds to the active site of DGAT-2 and blocks the transfer of fatty acids from diacylglycerol to triglycerides, which reduces the production of chylomicrons. This compound also inhibits hepatic lipase, which reduces the production and secretion of VLDLs. In addition, pradigastat has antimicrobial effects against bacteria such as Helicobacter pylori, which are known to cause gastric ulcers. Pradigastat also prevents viral replication by inhibiting human macrophages involved in lipid metabolism.
Aviso:
Nuestros productos están destinados únicamente para uso en laboratorio. Para cualquier otro uso, por favor contáctenos.
Marca:
Biosynth
Almacenamiento de larga duración:
Notas:
Propiedades químicas
Peso molecular:
455.47 g/mol
Fórmula:
C25H24F3N3O2
Pureza:
Min. 95%
InChI:
InChI=1S/C25H24F3N3O2/c26-25(27,28)23-12-10-21(15-30-23)31-20-9-11-22(29-14-20)19-7-5-18(6-8-19)17-3-1-16(2-4-17)13-24(32)33/h5-12,14-17,31H,1-4,13H2,(H,32,33)
Clave InChI:
InChIKey=GXALXAKNHIROPE-UHFFFAOYSA-N
SMILES:
O=C(O)CC1CCC(c2ccc(-c3ccc(Nc4ccc(C(F)(F)F)nc4)cn3)cc2)CC1
MDL:
Punto de fusión:
Punto de ebullición:
Punto de inflamabilidad:
Densidad:
Concentración:
EINECS:
Merck:
Código HS:
