PAR-2 (6-1) amide (mouse, rat) trifluoroacetate salt

CAS: 245329-01-5

Ref. 3D-FP109860

Información del producto

• Nombre: PAR-2 (6-1) amide (mouse, rat) trifluoroacetate salt
• Sinónimos: H-Leu-Arg-Gly-Ile-Leu-Ser-NH2 H-LRGILS-NH2
• CAS: 245329-01-5

Descripción

PAR-2 (6-1) amide is a proteolytic enzyme that is activated by inflammatory stimuli. It has been shown to be a major contributor to the pathogenesis of inflammatory bowel disease, and is found in neurons, the bowel, and pancreatic acinar cells. PAR-2 (6-1) amide activates proteases such as trypsin and chymotrypsin and also functions as an antimicrobial peptide. Activation of PAR-2 (6-1) amide leads to the cleavage of proteins at specific sites on their amino acid chains. This cleavage can lead to changes in protein conformation or function. PAR-2 (6-1) amide has been shown to increase endothelial cell proliferation and inhibit bacterial growth, but does not have any effect on cultured normal human skin fibroblasts.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 656.82 g/mol
• Fórmula: C₂₉H₅₆N₁₀O₇
• Pureza: Min. 95%