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Pyrido[2,3-D]-pyrimidin-4(3H)-one
CAS: 24410-19-3
Ref. 3D-FP13046
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Información del producto
- 4-Hydroxypyrido (2,3-d)pyrimidine
- pyrido[2,3-d]pyrimidin-4(1H)-one
- 3H,4H-pyrido[2,3-d]pyrimidin-4-one
Pyrido[2,3-D]-pyrimidin-4(3H)-one is a hydroxy derivative of formamide. It has been shown to inhibit the growth of cancer cells in vitro and in vivo by inhibiting DNA synthesis. Pyrido[2,3-D]-pyrimidin-4(3H)-one has also been shown to have potent antitumor activity against human prostate carcinoma cells. This compound has also been shown to increase the survival rate of mice bearing Ehrlich ascites tumor xenografts. Pyrido[2,3-D]-pyrimidin-4(3H)-one is able to suppress the production of topoisomerase II alpha protein and inhibit the proliferation of cultured lung cancer cells. This drug has also been shown to have cytotoxic effects on cultured leukemia cells.
Propiedades químicas
Consulta técnica sobre: 3D-FP13046 Pyrido[2,3-D]-pyrimidin-4(3H)-one
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