Pipobroman

CAS: 54-91-1

Ref. 3D-FP177387

Información del producto

• Nombre: Pipobroman
• Sinónimos: 1,1′-(1,4-Piperazinediyl)bis[3-bromo-1-propanone], 1,1′-(Piperazine-1,4-diyl)bis(3-bromopropan-1-one), 1,4-Bis(3-bromopropionyl)piperazine, 1,4-Di(3-bromopropionyl)piperazine, 1-Propanone, 1,1'-(1,4-piperazinediyl)bis[3-bromo-, 3-Bromo-1-[4-(3-bromopropanoyl)piperazin-1-yl]propan-1-one, A 1803, Amedel, N,N'-Bis(3-bromopropionyl)piperazine, Nsc-25154, Piperazine, 1,4-bis(3-bromopropionyl)-, Vercyte

Descripción

Pipobroman is an anti-cancer compound that belongs to the group of cytotoxic drugs. It is used in the treatment of solid tumours, and has shown a therapeutic effect on skin cancer when combined with other agents. Pipobroman binds to DNA and inhibits DNA synthesis. The drug also has been shown to inhibit the expression of Jak2 V617F, which is a mutation that is associated with hematologic response. Pipobroman has been shown to be effective against polycythaemia in mice and rats, as well as against erythrocytosis in dogs. Overall, pipobroman appears to be safe for use in humans but should not be administered for long periods of time due to its potential toxic effects on the liver and kidneys.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 356.05 g/mol
• Fórmula: C₁₀H₁₆Br₂N₂O₂
• Pureza: Min. 95%
• InChI: InChI=1S/C10H16Br2N2O2/c11-3-1-9(15)13-5-7-14(8-6-13)10(16)2-4-12/h1-8H2
• Clave InChI: InChIKey=NJBFOOCLYDNZJN-UHFFFAOYSA-N
• SMILES: O=C(CCBr)N1CCN(C(=O)CCBr)CC1