(1R)-(1S,2S,3R,5S)-Pinanediol-N-(N-pyrazinylphenylalaninoyl)-1-amino-3-methyl-butane-1-boronate
CAS: 205393-22-2
Ref. 3D-FP27051
250mg | 159,00 € | ||
500mg | 229,00 € |
Información del producto
- N-[(1S)-2-[[(1R)-1-[(3aS,4S,6S,7aR)-Hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]amino]-2-oxo-1- (phenylmethyl)ethyl]-2-pyrazinecarboxamide
- Bortezomib pinanediol ester
- N-[(1S)-2-[[(1R)-1-[(3As,4S,6S,7Ar)-Hexahydro-3A,5,5-Trimethyl-4,6-Methano-1,3,2-Benzodioxaborol-2-Yl]-3-Methylbutyl]Amino]-2-Oxo-1-(Phenylmethyl)Ethyl]-2-Pyrazinecarboxamide
- N-[(1S)-1-Benzyl-2-({(1R)-3-Methyl-1-[(1S,2S,6R,8S)-2,9,9-Trimethyl-3,5-Dioxa-4-Boratricyclo[6.1.1.0~2,6~]Dec-4-Yl]Butyl}Amino)-2-Oxoethyl]-2-Pyrazinecarboxamide
- Bortezomib Intermediates Iii
- Bortezomib Intermediate III
(1R)-(1S,2S,3R,5S)-Pinanediol-N-(N-pyrazinylphenylalaninoyl)-1-amino-3-methyl-butane-1-boronate is a boronic acid derivative that has been shown to have an antiproliferative effect on cancer cells. It is a biodegradable, water soluble drug with a low toxicity profile. The maximum tolerated dose has been established in vivo studies and it can be used as an imaging agent for diagnosis. (1R)-(1S,2S,3R,5S)-Pinanediol-N-(N-pyrazinylphenylalaninoyl)-1-amino-3-methyl-butane-1-boronate may be used to treat cancers such as breast cancer or leukemia. This drug targets the proteasome and inhibits its activity by binding to the active site of the 20s
Propiedades químicas
Consulta técnica sobre: 3D-FP27051 (1R)-(1S,2S,3R,5S)-Pinanediol-N-(N-pyrazinylphenylalaninoyl)-1-amino-3-methyl-butane-1-boronate
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