Primaquine diphosphate

CAS: 63-45-6

Ref. 3D-FP27162

Información del producto

• Nombre: Primaquine diphosphate
• Sinónimos: N4-(6-Methoxy-8-quinolinyl)-1,4-pentanediamine Phosphate, 1,4-Pentanediamine, N⁴-(6-methoxy-8-quinolinyl)-, phosphate (1:2), 8-(4-Amino-1-methylbutylamino)-6-methoxyquinoline di(dihydrogen phosphate), 8-(4-Amino-1-methylbutylamino)-6-methoxyquinoline diphosphate, Camden, Malquine, NSC 149765, N~4~-(6-methoxyquinolin-8-yl)pentane-1,4-diamine phosphate (1:2), Pharmaniaga, Primaquine Phosphate, Primaquine bisphosphate, Quinoline, 8-[(4-amino-1-methylbutyl)amino]-6-methoxy-, diphosphate, Quinoline, 8-[(4-amino-1-methylbutyl)amino]-6-methoxy-, phosphate (1:2), Wr 2975

Descripción

Primaquine is an antimalarial drug that belongs to the class of natural compounds. It works by inhibiting the activity of blood cells and preventing malaria parasites from reproducing in the red blood cells. Primaquine diphosphate (PQDP) is a recombinant cytochrome P450 enzyme that has been shown to have high activity against Mycobacterium tuberculosis and other bacteria. PQDP is a strong inhibitor of cytochrome P450 enzymes, which are involved in drug metabolism, leading to serious drug interactions with many drugs such as warfarin, phenytoin, or oral contraceptives. This recombinant enzyme also has been shown to bind to toll-like receptor 2 (TLR2) on macrophages and monocytes, which can lead to inflammation in the bowel.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 455.34 g/mol
• Fórmula: C₁₅H₂₇N₃O₉P₂
• Color/Forma: Powder
• InChI: InChI=1S/C15H21N3O.2H3O4P/c1-11(5-3-7-16)18-14-10-13(19-2)9-12-6-4-8-17-15(12)14;2*1-5(2,3)4/h4,6,8-11,18H,3,5,7,16H2,1-2H3;2*(H3,1,2,3,4)
• Clave InChI: InChIKey=GJOHLWZHWQUKAU-UHFFFAOYSA-N
• SMILES: COc1cc(NC(C)CCCN)c2ncccc2c1.O=P(O)(O)O.O=P(O)(O)O