1H-Pyrazol-3-yl boronic acid

CAS: 376584-63-3

Ref. 3D-FP50880

Información del producto

• Nombre: 1H-Pyrazol-3-yl boronic acid
• Sinónimos: 3-Pyrazole-boronic acid, Pyrazole-3-boronic acid, Pyrazole-2-Boronic Acid, 1H-pyrazol-3-ylboronic acid, 1H-Pyrazole-5-boronic acid, 1H-Pyrazole-3-boronic acid

Descripción

1H-Pyrazol-3-yl boronic acid is a reagent used in the synthesis of HIV protease inhibitors. It is also an inhibitor of serine proteases, such as HIV protease and papain. 1H-Pyrazol-3-yl boronic acid can be modified with a variety of functional groups to produce a lead compound for drug development. The compound has two isomers: 1H and 3H. The 3H isomer is not commercially available, but it can be produced by diazotization of 1H. The cyclic structure of 1H-pyrazol-3-yl boronic acid inhibits the protease activity by binding to the active site or by steric hindrance, which prevents substrate binding.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 111.9 g/mol
• Fórmula: C₃H₅BN₂O₂
• Pureza: Min. 95%