(R)-5-Hydroxymethyl tolterodine formate
CAS: 380636-49-7
Ref. 3D-FQA63649
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| 10mg | A consultar | ||
| 25mg | A consultar | ||
| 50mg | A consultar |
Información del producto
(R)-5-Hydroxymethyl tolterodine formate is a potent and selective activator of the human 5-HT3 receptor. It binds to the receptor with an affinity (Ki) of 0.2 nM and activates it with high potency (EC50 = 0.03 nM). The activation of the receptor leads to a fast increase in intracellular Ca2+ levels, which can be blocked by pretreatment with a specific antagonist. This compound also inhibits protein interactions with the 5-HT3 receptor, as shown by its ability to inhibit binding of peptides or antibodies to the receptor.
Propiedades químicas
Consulta técnica sobre: 3D-FQA63649 (R)-5-Hydroxymethyl tolterodine formate
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