rac trans-4-hydroxy glyburide

CAS: 23155-00-2

Ref. 3D-FR27584

Información del producto

• Nombre: rac trans-4-hydroxy glyburide
• Sinónimos: 5-Chloro-N-[2-[4-[[[[(4-hydroxycyclohexyl)amino]carbonyl]amino]sulfonyl]phenyl)ethyl]-2-methoxybenzamide4'-Hydroxyglibenclamide, 4-trans-Hydroxycyclohexyl glyburide, 4-trans-Hydroxyglibenclamide, 5-Chloro-N-[2-[4-[[[[(trans-4-hydroxycyclohexyl)amino]carbonyl]amino]sulfonyl]phenyl]ethyl]-2-methoxybenzamide, Benzamide,5-chloro-N-[2-[4-[[[[(4-hydroxycyclohexyl)amino]carbonyl]amino]sulfonyl]phenyl]ethyl]-2-methoxy-,trans-, N-[4-[b-(2-Methoxy-5-chlorobenzamido)ethyl]benzenesulfonyl]-N'-(trans-4-hydroxycyclohexyl)urea, Urea, 1-[[p-[2-(5-chloro-o-anisamido)ethyl]phenyl]sulfonyl]-3-(4-hydroxycyclohexyl)-, trans-, Urea,1-[[p-[2-(5-chloro-o-anisamido)ethyl]phenyl]sulfonyl]-3-(4-hydroxycyclohexyl)-,trans- (8CI), trans-4-Hydroxyglyburide, trans-N-4-[2-(5-Chloro-2-methoxybenzamido)ethyl]phenylsulfonyl-N'-(4-hydroxycyclohexyl)urea, Benzamide, 5-chloro-N-[2-[4-[[[[(trans-4-hydroxycyclohexyl)amino]carbonyl]amino]sulfonyl]phenyl]ethyl]-2-methoxy-

Descripción

Rac trans-4-hydroxy glyburide is a drug that belongs to the class of sulfonylureas. It is used for the treatment of type 2 diabetes mellitus and has been shown to increase insulin secretion from pancreatic beta cells. The drug is metabolized in the liver by esterases, glucuronidases, or cytochrome P450 enzymes, with metabolites being excreted in urine samples. Sorafenib is an anti-cancer drug that inhibits tumor growth by inhibiting angiogenesis, cell proliferation, and metastasis. There are significant interactions between these two drugs that may lead to a decrease in efficacy. Rac trans-4-hydroxy glyburide has been shown to be hydrolyzed by esterases and terminal half life ranges from 10 hours to 17 hours depending on urinary pH levels.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 510 g/mol
• Fórmula: C₂₃H₂₈ClN₃O₆S
• Pureza: Min. 95%