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Ramiprilat diketopiperazine
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Ramiprilat diketopiperazine

CAS: 108736-10-3

Ref. 3D-FR27679

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Información del producto

Nombre:
Ramiprilat diketopiperazine
Sinónimos:
  • [3S-[2(R*),3a,5a-b,8a-b,9a-b]]-Decahydro-3-methyl-1,4-dioxo-a-(2-phenylethyl)-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazine-2-acetic acid
  • [3S-[2(R*),3a,5ab,8ab,9ab]]-Decahydro-3-methyl-1,4-dioxo-a-(2-phenylethyl)-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazine-2-acetic Acid
  • [3S-[2(R*),3a,5a,8a,9a]]-Decahydro-3-methyl-1,4-dioxo-a-(2-phenylethyl)-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazine-2-acetic Acid
Descripción:

Ramiprilat diketopiperazine is a drug that is metabolized by glucuronidation. It is an analog of ramipril, which is a member of the angiotensin-converting enzyme (ACE) inhibitors. Ramiprilat diketopiperazine has been shown to be clinically effective in reducing blood pressure and improving left ventricular function in patients with chronic heart failure. The reanalysis and validation of the bioanalytical method for analysis of ramiprilat diketopiperazine have been completed, and the method was validated for use in clinical studies. The analytes were measured using chromatography with ultraviolet detection or with liquid chromatography-mass spectrometry-mass spectrometry. The method development for the analysis of glucuronide metabolites has also been completed, and these metabolites were quantified using high performance liquid chromatography with UV detection or with gas chromatography-mass spectrometry-mass spectrometry.

Aviso:
Nuestros productos están destinados únicamente para uso en laboratorio. Para cualquier otro uso, por favor contáctenos.
Marca:
Biosynth
Almacenamiento de larga duración:
Notas:

Propiedades químicas

Peso molecular:
370.44 g/mol
Fórmula:
C21H26N2O4
Pureza:
Min. 95%
InChI:
InChI=1S/C21H26N2O4/c1-13-19(24)23-16-9-5-8-15(16)12-18(23)20(25)22(13)17(21(26)27)11-10-14-6-3-2-4-7-14/h2-4,6-7,13,15-18H,5,8-12H2,1H3,(H,26,27)/t13-,15-,16-,17-,18-/m0/s1
Clave InChI:
InChIKey=DZRWPCCIYKIPJW-HILJTLORSA-N
SMILES:
C[C@H]1C(=O)N2[C@@H](C[C@@H]3CCC[C@@H]32)C(=O)N1[C@@H](CCc1ccccc1)C(=O)O
MDL:
Punto de fusión:
Punto de ebullición:
Punto de inflamabilidad:
Densidad:
Concentración:
EINECS:
Merck:
Código HS:

Información de peligrosidad

Número UN:
Cantidad exceptuada (EQ):
Clase:
Frases H:
Frases P:
Prohibido volar:
Información de peligrosidad:
Grupo de empaquetado:
Cantidad limitada (LQ):

Consulta sobre el producto descatalogado: 3D-FR27679 Ramiprilat diketopiperazine

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