SPARC (119-122) (mouse) acetate salt

CAS: 155149-79-4

Ref. 3D-FS108680

Información del producto

• Nombre: SPARC (119-122) (mouse) acetate salt
• Sinónimos: H-Lys-Gly-His-Lys-OH H-KGHK-OH

Descripción

SPARC (119-122) (mouse) is an acetate salt of H-Lys-Gly-His-Lys-OH. SPARC (119-122) has been shown to be a mimetic of the c-terminal region of the protein SPARC and can bind to many metal ions including Zn2+, Mn2+, Cu2+, Co2+, Ni2+ and Mg2+. The binding affinity for these metals is dose dependent, with saturation occurring at high concentrations. This property may make this compound a therapeutic target for drug discovery strategies.

SPARC (119-122) has been shown to inhibit lisinopril, an angiotensin converting enzyme inhibitor that is used as a drug to treat hypertension and heart failure. Lisinopril inhibits the conversion of angiotensin I into angiotensin II which causes vasoconstriction and increases blood pressure. In in vitro studies, SPARC (119-122)

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 468.55 g/mol
• Fórmula: C₂₀H₃₆N₈O₅
• Pureza: Min. 95%