Salinosporamide A

CAS: 437742-34-2

Ref. 3D-FS36376

Información del producto

• Nombre: Salinosporamide A
• Sinónimos: (1R,4R,5S)-4-(2-Chloroethyl)-1-[(S)-(1S)-2-cyclohexen-1-ylhydroxymethyl]-5-methyl-6-oxa-2-azabicyclo[3.2.0]heptane-3,7-dione, (-)-Salinosporamide A, NPI 0052, 6-Oxa-2-azabicyclo[3.2.0]heptane-3,7-dione, 4-(2-chloroethyl)-1-[(S)-(1S)-2-cyclohexen-1-ylhydroxymethyl]-5-methyl-, (1R,4R,5S)-

Descripción

Salinosporamide A is a novel anti-cancer compound that belongs to the class of aldol cyclization reaction. It is an irreversible inhibitor of protein kinase C and has been shown to inhibit growth factor-induced cell proliferation in vitro. Salinosporamide A also inhibits the production of nitric oxide, which may be involved in the inhibition of growth factor-induced cell proliferation in vitro. Salinosporamide A is selective for cAMP-dependent protein kinase, but not for other protein kinases such as Ca2+/calmodulin-dependent protein kinase II and Ca2+/calmodulin-dependent protein kinase IV. Salinosporamide A has also shown effectiveness against infectious diseases caused by bacteria and fungi. It acts by inhibiting the synthesis of DNA, RNA, and proteins.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 313.78 g/mol
• Fórmula: C₁₅H₂₀ClNO₄
• Pureza: Min. 95%
• Color/Forma: White Powder