BMH-22
CAS: 309726-06-5
Ref. 3D-FT121861
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Información del producto
- 2,4,7,9-Tetramethylbenzo[b]-1,8-naphthyridin-5-amine
- Benzo[b][1,8]naphthyridin-5-amine, 2,4,7,9-tetramethyl- (9CI)
2,4,7,9-Tetramethylbenzo[b]-1,8-naphthyridin-5-amine (TMBA) is a potent agent that inhibits the protein synthesis of cancer cells and other cells. TMBA binds to the ribosomal protein L6 in the ribosome and disrupts the function of the ribosome. TMBA also interacts with ribosomal RNA (rRNA) and prevents its association with proteins involved in translation. TMBA interacts with integrator subunits to stabilize ribosomes and prevent their degradation by proteases. It is also capable of stabilizing cellular DNA against damage caused by reactive oxygen species. TMBA has been shown to be effective against drug resistant cancer cells.
Propiedades químicas
Consulta técnica sobre: 3D-FT121861 BMH-22
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