3,4,5-Trifluorophenylalanine
CAS: 261952-26-5
Ref. 3D-FT78984
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Información del producto
- 3,4,5-Trifluoro-L-phenylalanine
- L-Phenylalanine, 3,4,5-trifluoro-
3,4,5-Trifluorophenylalanine is a fluorinated amino acid that has been shown to have a protective effect against Alzheimer's disease. 3,4,5-Trifluorophenylalanine binds to the hydrophobic region of beta-amyloid and inhibits its aggregation into plaques. It also has a spectrum of activity against diaminopyrimidine sequences, which are hallmarks of alzheimer's disease. This compound is synthesized by the addition of hydrogen chloride onto 3-hydroxyphenylpyruvic acid (3HPP). The synthesis is catalyzed by hydroxylase enzymes in the liver. 3,4,5-Trifluorophenylalanine is metabolized by the enzyme valine hydroxylase and excreted as an inactive form in urine.
Propiedades químicas
Consulta técnica sobre: 3D-FT78984 3,4,5-Trifluorophenylalanine
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