3-Vinyl-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one

CAS: 832747-59-8

Ref. 3D-FV28703

Información del producto

• Nombre: 3-Vinyl-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
• Sinónimos: 3-Ethenyl-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one

Descripción

3-Vinyl-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one (RIS) is a neuroleptic drug that belongs to the class of phenothiazine. RIS is used for the treatment of schizophrenia and other psychotic disorders. The chemical synthesis process of RIS involves a four step sequence: 1) Nucleophilic substitution of 3,5 dimethoxyphenylacetonitrile with methyl iodide in an inert solvent such as tetrahydrofuran; 2) Protection of the reactive amino group by forming an acetal with ethylene glycol; 3) Alkylation of the acetal with propargyl bromide in the presence of a base such as sodium hydride; 4) Hydrolysis and decarboxylation of the resulting compound.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 190.24 g/mol
• Fórmula: C₁₁H₁₄N₂O
• Pureza: Min. 95%
• InChI: InChI=1S/C11H14N2O/c1-3-9-8(2)12-10-6-4-5-7-13(10)11(9)14/h3H,1,4-7H2,2H3
• Clave InChI: InChIKey=UPHZNIPFWOLSGX-UHFFFAOYSA-N
• SMILES: C=Cc1c(C)nc2n(c1=O)CCCC2